Dr. José R. Donoso

Institut für Neuroinformatik
Ruhr-Universität Bochum
Universitätsstraße 150
Building NB, Room NB 3/28
D-44801 Bochum
Germany
Computational Neuroscience

Groups

RESEARCH

I’m currently focusing on the neural processes underlying extinction learning, and on models of hippocampal function.

BACKGROUND

I graduated as an Electrical Engineer (Universidad de Chile) and obtained a M.Sc. in Cognitive and Computational Neuroscience (University of Sheffield). During my doctoral studies (Humboldt-Universität zu Berlin), I focused on the mechanisms responsible for the generation of fast oscillations (90–220 Hz) in the hippocampus, which have been implicated in the consolidation of recently acquired memories. There, I combined computational models with experiments in vitro to clarify several previously unexplained features of these oscillations.

Donoso JR, Maier N, Schmitz D, Kempter R (in review) Hippocampal ripples and inhibition-first network models:  Frequency dynamics and response to GABA modulators.

Klein AS, Donoso JR, Kempter R, Schmitz D, Beed P (2016) Early Cortical Changes in Gamma Oscillations in Alzheimer’s Disease. Front Sys Neurosci. 10.

Pangalos M, Donoso JR, Winterer J, Zivkovic AR, Kempter R, Maier N, Schmitz D (2013) Recruitment of oriens-lacunosum-moleculare interneurons during hippocampal ripples. PNAS USA. 110:4398-403.

Perez CA, Donoso JR, Medina LE (2010) A critical experimental study of the classical tactile threshold theory. BMC Neurosci. 11:76.

Perez CA, Cohn TE, Medina LE, Donoso JR (2007) Coincidence-enhanced stochastic resonance: Experimental evidence challenges the psychophysical theory behind stochastic resonance. Neurosci Lett. 424:31-5.